Title斑点追踪技术评价高血压患者左心房功能的早期改变
Other TitlesEarly detection of abnormal left atrial function by speckle-tracking in hypertensive patients
Authors杨颖
吴国祥
张宝娓
齐丽彤
陈峰
于荣辉
霍勇
Affiliation100034,北京大学第一医院心内科
福建医科大学附属南平市第一医院心内科
Keywords超声心动描记术
高血压
心房功能,左
斑点追踪显像
Echocardiography
Hypertension
Atrial function,left
Speckle tracking imaging
Issue Date2012
Publisher中华超声影像学杂志
Citation中华超声影像学杂志.2012,21,(8),661-664.
Abstract目的 探讨斑点追踪技术评价高血压患者左心房功能早期受损可行性.方法 对154例左房容积指数<28 ml/m2的高血压患者与64例对照者行超声心动图检查并存储图像.采用二维斑点追踪技术,离线测量并比较两组心尖四腔观左房整体长轴舒张晚期应变(Sa)、收缩期应变(Ss)、总应变( Stot=Sa+ Ss),及舒张晚期应变率(SRa)、收缩期应变率(SRs)、舒张早期应变率(SRe).结果 高血压组反映左房储存器功能的Stot与SRs、反映通道功能的Ss与SRe均较对照组明显减低;反映左房泵功能的Sa与SRa两组无差别.Ss、Stot、SRe与高血压及高血压持续时间呈显著负相关.结论 左房大小正常的高血压患者左房储存器功能与通道功能减低,泵功能无变化.斑点追踪技术可用于早期左房功能异常的评价.
Objective To evaluate the feasibility of speckle-tracking echocardiography in detecting left atrial (LA) function impairment in early hypertensive (HT) patients.Methods Echocardiography was performed in 154 HT patients with LA volume index <28 ml/m2 and 64 age/gender-matched control subjects.LA global longitudinal strain in late diastole (Sa),systole (Ss),and total strain (Stot =Sa + Ss),strain rate in late diastole (SRa),systole (SRs),and early diastole (SRe) were measured using off-line speckle-tracking analyzing software in apical 4 chamber view.Results Both parameters reflecting LA reservoir function [Stot (23.7 ± 6.0) % vs (25.7 ± 5.9) %,p =0.03 and SRs ( 1.2 ± 0.3) s- 1 vs ( 1.3 ±0.3) s-1,P =0.03]and conduit function [Ss (12.0 ± 5.1)% vs (14.0±5.7)%,P =0.02 and SRe (1.0 ± 0.4)s- 1 vs ( 1.2 ± 0.4)s- 1,p <0.001 ]decreased significantly in HT group than control,while LA pump function parameters (Sa and SRa) had no differences.Ss,Stot and SRe correlated significantly with HT and HT duration.Conclusions LA phasic function are impaired in HT patients with normal LA size.Speckle tracking echocardiography is a promising tool for the early detection of LA dysfunction.
URIhttp://hdl.handle.net/20.500.11897/123989
ISSN1004-4477
DOI10.3760/cma.j.issn.1004-4477.2012.08.007
Indexed中文核心期刊要目总览(PKU)
中国科技核心期刊(ISTIC)
中国科学引文数据库(CSCD)
Appears in Collections:第一医院

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