Title螺内酯对老年冠心病心力衰竭患者某些体液因子的影响
Other TitlesThe Effect of Spironolactone on Some Neurohormonal Factors in Elderly Patients Suffering Cardiac Insufficiency Secondary to Coronary Heart Disease
Authors李帮清
吴淳
胡大一
孙宁玲
Affiliation北京大学人民医院心内科,北京,100044
Keywords螺内酯
心力衰竭
儿茶酚胺
Issue Date2005
Publisher中国医药导刊
Citation中国医药导刊.2005,7,(1),49,52.
Abstract目的:探讨螺内酯对老年冠心病心力衰竭患者血浆儿茶酚胺、PRA、血管紧张素Ⅱ及醛固酮的影响.方法:入选32例老年冠心病心力衰竭患者,随机分入螺内酯组与对照组,各16例,用螺内酯治疗前与治疗一个月时,用高效液相色谱方法测定血浆去甲肾上腺素、肾上腺素,同时采用均相竞争放射免疫方法检测血浆PRA、血管紧张素-Ⅱ与醛固酮.结果:治疗1月螺内酯组血浆去甲肾上腺素、肾上腺素明显低于治疗前,也低于对照组.结论:螺内酯可明显抑制老年冠心病心力衰竭患者的儿茶酚胺水平.
URIhttp://hdl.handle.net/20.500.11897/133936
ISSN1009-0959
DOI10.3969/j.issn.1009-0959.2005.01.023
Appears in Collections:人民医院

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