| Title | Development of an expedient intramolecular Pauson-Khand reaction approach to stereoselectively construct the trans-decalin with a C1 quaternary chiral center |
| Authors | Shi, Li-Li Shen, Hong-Juan Fang, Li-Chao Huang, Jun Li, Chuang-Chuang Yang, Zhen |
| Affiliation | Peking Univ, Shenzhen Grad Sch, Lab Chem Genom, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China. Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China. Peking Univ, BNLMS, Beijing 100871, Peoples R China. Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China. |
| Keywords | FUSARIUM TOXIN EQUISETIN DIELS-ALDER REACTION DIRECTING GROUP STRATEGY BOTTOM-HALF ENANTIOSELECTIVE SYNTHESIS ACYCLIC STEREOCONTROL ASYMMETRIC-SYNTHESIS FORMAL SYNTHESIS N-OXIDE CHLOROTHRICOLIDE |
| Issue Date | 2013 |
| Publisher | chemical communications |
| Citation | CHEMICAL COMMUNICATIONS.2013,49,(78),8806-8808. |
| Abstract | Stereoselective synthesis of the trans-decalin subunit with a defined C1 quaternary chiral center has been achieved by the Pauson-Khand reaction (PKR) as a key step. The developed chemistry offers an alternative to the IMDA reaction that has been used for the syntheses of trans-decalin based biologically active natural products. |
| URI | http://hdl.handle.net/20.500.11897/190391 |
| ISSN | 1359-7345 |
| DOI | 10.1039/c3cc45170d |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 深圳研究生院待认领 化学与分子工程学院 生命科学学院 生物有机与分子工程教育部重点实验室 |
