Title大气可吸入颗粒物与心脑血管疾病急诊关系的病例交叉研究
Other TitlesAssociation between the concentration of particulate matters and the hospital emergency room visits for circulatory diseases: a case-crossover study
Authors郭玉明
刘利群
陈建民
杨敏娟
Wichmann
潘小川
Affiliation北京大学医学部公共卫生学院劳动卫生与环境卫生学系,100191
北京大学第三医院病案室
GSF-National Research Centre for Environment and Health,Munich German
Keywords心脑血管疾病 可吸入颗粒物 病例交叉研究 Circulatory diseases Particulate matter Case-crossover study
Issue Date2008
Publisher中华流行病学杂志
Citation中华流行病学杂志.2008,29,(11),1064-1068.
Abstract目的 探讨北京市大气可吸入颗粒物污染(PM10)对心腩血管疾病急诊的影响.方法 收集北京大学第三医院急诊科心脑血管疾病急诊资料和北京市环境监测中心大气污染物数据,应用时间分层的病例交叉设计研究方法进行数据分析.结果 无滞后单向同顾性1:4配对病例交叉研究的效应值(OR值)最大,在控制所选PM10当日气温、相对湿度影响的情况下,PM10浓度每提高10μg/m3与心脑血管疾病急诊(ICD-10:I00-I99)、冠心病急诊(ICD-10:120-125)、心律失常急诊(ICD-10:147-149)、心衰急诊(ICD-10:150)和脑血管疾病急诊(ICD-10:160-169)的OR值分别为1.006(95%CI:1.003~1.008)、1.003(95%CI:0.996~1.010)、1.005(95%CI:0.997~1.013)、1.019(95%CI:1.005~1.033)、1.003(95%CI:0.998~1.007),其中PM10与总心脑血管疾病急诊和心衰急诊的关联有统计学意义(P<0.05).结论 大气PM10污染物浓度升高可导致总心脑血管疾病急诊和心衰急诊增加.
To explore the association between the concentration of particulate matters with an aerodynamic diameter of < 10 microm (PM(10)) and the hospital emergency room visits for circulatory diseases (International Classification of Diseases, tenth vision ICD-10:I00-I99) in Beijing, China.We collected data for daily hospital emergency room visits of circulatory diseases (ICD-10:I00-I99) from Peking University Third Hospital and from the ambient air PM(10) through the Beijing Municipal Environmental Monitoring Center. A time-stratified case-crossover design was used to evaluate associations between circulatory disease health outcomes and PM(10).The no-lagged unidirectional case-crossover design with 1:4 matched pairs had the highest odds ratios (ORs) between PM(10) and the hospital emergency room visits for circulatory diseases. After adjusting the temperature and the relative humidity, a 10 microg/m(3) increased in the PM(10) were found associated with the emergency room visits on value of ORs of 1.006(95%CI: 1.003 - 1.008) for the total circulatory diseases (ICD-10:I00-I99), 1.003 (95%CI: 0.996 - 1.010) for coronary heart disease (ICD-10:I20-I25), 1.005 (95%CI: 0.997 - 1.013) for cardiac arrhythmia (ICD-10:I47-I49), 1.019 (95%CI: 1.005 - 1.033) for heart failure disease (ICD-10:I50), and 1.003 (95%CI: 0.998 - 1.007) for cerebrovascular diseases (ICD-10:I60-I69), respectively.These findings suggested that elevated levels of ambient PM(10) were positively associated with hospital emergency room visits for the total number of circulatory diseases and heart failure disease.
URIhttp://hdl.handle.net/20.500.11897/197280
ISSN0254-6450
DOI10.3321/j.issn:0254-6450.2008.11.003
IndexedPubMed
中文核心期刊要目总览(PKU)
中国科技核心期刊(ISTIC)
中国科学引文数据库(CSCD)
Appears in Collections:公共卫生学院
第三医院

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