TitleAll-in-One azides: empowered click reaction for in vivo labeling and imaging of biomolecules
AuthorsSu, Yaning
Li, Li
Wang, Haibin
Wang, Xiaochen
Zhang, Zhiyuan
AffiliationBeijing Normal Univ, Coll Life Sci, Beijing 100875, Peoples R China.
Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China.
Natl Inst Biol Sci NIBS, Beijing 102206, Peoples R China.
Collaborat Innovat Ctr Canc Med, Beijing 102206, Peoples R China.
Natl Inst Biol Sci NIBS, Beijing 102206, Peoples R China.
Zhang, ZY (reprint author), Collaborat Innovat Ctr Canc Med, Beijing 102206, Peoples R China.
KeywordsALKYNE CYCLOADDITION
KINASE INHIBITORS
CHEMISTRY
BIOCONJUGATION
SELECTIVITY
Issue Date2016
PublisherCHEMICAL COMMUNICATIONS
CitationCHEMICAL COMMUNICATIONS.2016,52,(10),2185-2188.
AbstractWe designed and synthesized All-in-One (AIO) reactive azide reagents for bioorthogonal reactions with highly efficient Cu(I) ligand moieties, an azido group, and functional tags for imaging or purification. The AIO reagents displayed fast and efficient click ligation and can be applied in a wide range of in vivo systems.
URIhttp://hdl.handle.net/20.500.11897/435530
ISSN1359-7345
DOI10.1039/c5cc08466k
IndexedSCI(E)
PubMed
Appears in Collections:生命科学学院

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