| Title | All-in-One azides: empowered click reaction for in vivo labeling and imaging of biomolecules |
| Authors | Su, Yaning Li, Li Wang, Haibin Wang, Xiaochen Zhang, Zhiyuan |
| Affiliation | Beijing Normal Univ, Coll Life Sci, Beijing 100875, Peoples R China. Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China. Natl Inst Biol Sci NIBS, Beijing 102206, Peoples R China. Collaborat Innovat Ctr Canc Med, Beijing 102206, Peoples R China. Natl Inst Biol Sci NIBS, Beijing 102206, Peoples R China. Zhang, ZY (reprint author), Collaborat Innovat Ctr Canc Med, Beijing 102206, Peoples R China. |
| Keywords | ALKYNE CYCLOADDITION KINASE INHIBITORS CHEMISTRY BIOCONJUGATION SELECTIVITY |
| Issue Date | 2016 |
| Publisher | CHEMICAL COMMUNICATIONS |
| Citation | CHEMICAL COMMUNICATIONS.2016,52,(10),2185-2188. |
| Abstract | We designed and synthesized All-in-One (AIO) reactive azide reagents for bioorthogonal reactions with highly efficient Cu(I) ligand moieties, an azido group, and functional tags for imaging or purification. The AIO reagents displayed fast and efficient click ligation and can be applied in a wide range of in vivo systems. |
| URI | http://hdl.handle.net/20.500.11897/435530 |
| ISSN | 1359-7345 |
| DOI | 10.1039/c5cc08466k |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 生命科学学院 |
