Title | Adjustment of systematic biases in PICR model for DNA copy number estimation based on SNP microarray data |
Authors | 汪泉 曲江寒 程晓行 康永健 钱敏平 邓明华 |
Affiliation | 北京大学理论生物学中心 北京大学元培学院 北京大学数学科学学院 北京大学统计科学中心 |
Keywords | preprocessing Probe DNA eliminate adjusted Number consistently adjustment |
Issue Date | 2010 |
Citation | 第四届全国生物信息学与系统生物学学术大会.. |
Abstract | Affymetrix's SNP array has been widely used for single-nucleotide polymorphism (SNP) genotyping and DNA Copy Number Variation(CNV) detection.Although various methods developed for this field perform well, most of them ignored the binding between allelic probe and off-target DNA sequences in data ... |
URI | http://hdl.handle.net/20.500.11897/46982 |
Appears in Collections: | 生命科学学院 元培学院 数学科学学院 |