Title | 抗血管内皮生长因子在眼科治疗中的趋势与挑战 |
Other Titles | Progression and challenge of anti-vascular endothelial growth factor therapy in retinal neovascular disease |
Authors | 黎晓新 白玉婧 |
Affiliation | 100044,北京大学人民医院眼科中心暨眼科研究所视觉损伤与修复(北京大学)教育部重点实验室视网膜脉络膜疾病诊治研究北京市重点实验室 |
Keywords | 血管内皮生长因子A 眼底 新生血管化,病理性 黄斑变性 糖尿病视网膜病变 Vascular endothelial growth factor A Fundus oculi Neovascularization,pathologic Macular degeneration Diabetic retinopathy |
Issue Date | 2016 |
Publisher | 中华眼科杂志 |
Citation | 中华眼科杂志.2016,52(5),321-324. |
Abstract | 眼内抗VEGF的靶向给药已经成为血管性疾病治疗领域中令人瞩目的焦点,为重塑患者视力、降低致盲率发挥了重要作用.随着对眼底血管性疾病发病机制研究及临床试验探索的不断发展和提高,抗新生血管药物的靶向治疗在诊疗策略上也在不断进行优化,而与此同时抗VEGF治疗引发的副作用也逐渐显露.本文针对抗VEGF在眼底新生血管性疾病治疗中的趋势与挑战进行分析和总结,以飨读者. Anti-vascular endothelial growth factor (VEGF) therapy as an effective therapeutic method has been a standard treatment strategy in retinal neovascular disease,contributing to restore vision and reduce the prevalence of blindness.With the research on the pathogenesis of retinal neovascular disease and implementation of clinical trials,anti-VEGF therapy is continuously optimized.Meanwhile,the complications after the use of anti-angiogenetic drugs are exposed.The present article summarizes the update and challenge of anti-VEGF therapy in retinal neovascular disease. |
URI | http://hdl.handle.net/20.500.11897/493899 |
ISSN | 0412-4081 |
DOI | 10.3760/cma.j.issn.0412-4081.2016.05.001 |
Indexed | 中文核心期刊要目总览(PKU) 中国科技核心期刊(ISTIC) 中国科学引文数据库(CSCD) |
Appears in Collections: | 人民医院 |