Title原发灶不明转移癌基因表达谱分析技术进展
Other TitlesAdvances in gene expression profiling of metastases from unidentified primary tumor
Authors韩倩
林连君
Affiliation北京大学第一医院老年科 北京 100034
Keywords原发灶不明转移癌
基因表达谱分析技术
诊断进展
Cancer of unknown primary sites( CUP)
Gene expression profiling( GEP)
Progress in di-agnosis
Issue Date2017
Publisher实用肿瘤学杂志
Citation实用肿瘤学杂志. 2017, 31(6), 554-558.
Abstract原发灶不明转移癌(CUP)是一类经组织病理学证实为转移性,但经多种临床诊疗手段无法明确原发灶的肿瘤.明确肿瘤原发部位是CUP诊断的第一步,组织病理学、免疫组织化学技术、PET/CT都是临床常用的诊疗手段.基因表达谱分析技术是近年新兴的一种诊断原发灶的方法,具有较高的诊断准确率、敏感性和特异性,有望实现CUP患者的个体化治疗.
Primary lesions unknown metastatic cancer ( CUP) is a class of histopathologically confirmed metastases. However,a variety of clinical diagnosis and treatment can not clear the primary tumor. The identifica-tion of tumor primary site is the first step in the diagnosis of CUP. The histopathology,immunohistochemistry and PET /CT are commonly used clinical diagnosis and treatment. Gene expression profiling technique is a new meth-od for the diagnosis of primary tumor in recent years. It has high diagnostic accuracy,sensitivity and specificity, and is expected to achieve individual treatment of patients with CUP.
URIhttp://hdl.handle.net/20.500.11897/499098
ISSN1002-3070
DOI10.11904/j.issn.1002-3070.2017.06.014
Appears in Collections:第一医院

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