Title利用中期FISH发现伴t(8;17)急性髓系白血病一例
Other TitlesA rare t(8;17) chromosomal translocation in a case of acute myeloid leukemia detected by metaphase-FISH
Authors王艳芳
刘佳
万伟
王化
张朕豪
王晶
克晓燕
Affiliation100191,北京大学第三医院血液科
Keywords@@
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Issue Date2018
Publisher中华血液学杂志
Citation中华血液学杂志. 2018, 39(1), 77.
Abstract患者,女,76岁,主因间断晕厥15d,发现WBC升高3d入院.入院时血常规:WBC 255.48× 109/L,HGB 67 g/L,PLT26×109/L,幼稚细胞占0.79.骨髓象:增生明显活跃,粒系占0.900,原始粒细胞占0.580,可见Auer小体,POX染色阳性,非特异性酯酶染色阴性.流式细胞术检测免疫表型:CD13(+)、CD33(+)、CD64(+)、CD123(+)、CD11c(+)、cMPO(+),不表达CD7、CD56、CD10、CD3、CD19,为异常早期髓系细胞,比例为49.75%.PML-RARα等相关白血病融合基因检测阴性.染色体核型:46,XX,t(15;8;17) (q22;q24;q21)[20](图1).
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URIhttp://hdl.handle.net/20.500.11897/510098
ISSN0253-2727
DOI10.3760/cma.j.issn.0253-2727.2018.01.021
IndexedPubMed
Medline
Appears in Collections:第三医院

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