TitleF-18-FDG PET/CT in a Patient With Thymoma-Associated Paraneoplastic Polymyositis
AuthorsFu, Zhanli
Chen, Guoqian
Chen, Xueqi
Li, Qian
AffiliationPeking Univ, Hosp 1, Dept Nucl Med, 8 Xishiku St, Beijing 100034, Peoples R China
Wenzhou Med Univ, Affiliated Hosp 1, Dept Neurol, Wenzhou, Peoples R China
Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02115 USA
Issue DateFeb-2020
AbstractA 43-year-old woman presented with progressive muscle weakness and myalgia for 1 month. Laboratory tests revealed the elevation of myogenic enzymes. MRI of the thighs demonstrated a pattern of edema for inflammatory myopathy. Electromyography showed diffuse myopathic disorder, and muscle biopsy indicated polymyositis. F-18-FDG PET/CT was performed to investigate the potential paraneoplastic syndrome and revealed a soft tissue lesion with F-18-FDG avidity in the right anterior mediastinum, as well as diffusely increased activity throughout the body muscles. The patient's symptoms and biochemical abnormalities were gradually relieved after the tumor resection, and the histopathology indicated a type AB thymoma.
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