| Title | Long-term ambient ozone exposure and incident cardiovascular diseases: National cohort evidence in China |
| Authors | Zhu, Lifeng Fang, Jiaying Yao, Yao Yang, Zhiming Wu, Jing Ma, Zongwei Liu, Riyang Zhan, Yu Ding, Zan Zhang, Yunquan |
| Affiliation | Wuhan Univ Sci & Technol, Inst Social Dev & Hlth Management, Sch Publ Hlth, Hubei Prov Key Lab Occupat Hazard Identificat & Co, Wuhan 430065, Peoples R China Huadu Dist Peoples Hosp Guangzhou, Guangzhou 510800, Peoples R China Peking Univ, China Ctr Hlth Dev Studies, Beijing 100871, Peoples R China Univ Sci & Technol Beijing, Sch Econ & Management, Beijing 100083, Peoples R China Nanjing Univ, Sch Environm, State Key Lab Pollut Control & Resource Reuse, Nanjing 210023, Peoples R China Sichuan Univ, Dept Environm Sci & Engn, Chengdu 610065, Peoples R China Baoan Cent Hosp Shenzhen, Shenzhen 518102, Peoples R China Wuhan Univ Sci & Technol, Sch Publ Hlth, Wuhan 430065, Peoples R China |
| Keywords | AIR-POLLUTION GLOBAL BURDEN MORTALITY PREVALENCE TRENDS PM2.5 |
| Issue Date | Jun-2024 |
| Publisher | JOURNAL OF HAZARDOUS MATERIALS |
| Abstract | Background: Long-term ozone (O3) exposure has been associated with cardiovascular disease (CVD) mortality in mounting cohort evidence, yet its relationship with incident CVD was poorly understood, especially in low- and middle-income countries (LMICs) experiencing high ambient air pollution. Methods: We carried out a nationwide perspective cohort study from 2010 through 2018 by dynamically enrolling 36948 participants across Chinese mainland. Warm-season (April-September) O3 concentrations were estimated using satellite-based machine-learning models with national coverage. Cox proportional hazards model with time-varying exposures was employed to evaluate the association of long-term O3 exposure with incident CVD (overall CVD, hypertension, stroke, and coronary heart disease [CHD]). Assuming causality, a |
| URI | http://hdl.handle.net/20.500.11897/712268 |
| ISSN | 0304-3894 |
| DOI | 10.1016/j.jhazmat.2024.134158 |
| Indexed | SCI(E) |
| Appears in Collections: | 国家发展研究院 |
